Nasal mucosal dysplasia induced by topical corticosteroids with benzalkonium chloride
نویسندگان
چکیده
منابع مشابه
Corneal neurotoxicity due to topical benzalkonium chloride.
PURPOSE The aim of this study was to determine and characterize the effect of topical application of benzalkonium chloride (BAK) on corneal nerves in vivo and in vitro. METHODS Thy1-YFP+ neurofluorescent mouse eyes were treated topically with vehicle or BAK (0.01% or 0.1%). Wide-field stereofluorescence microscopy was performed to sequentially image the treated corneas in vivo every week for ...
متن کاملA rabbit dry eye model induced by topical medication of a preservative benzalkonium chloride.
PURPOSE To establish a rabbit dry eye model with topical medication of the ocular preparation preservative benzalkonium chloride (BAC). METHODS Sixteen white rabbits were used. One eye of each rabbit was chosen randomly for topical administration of 0.1% BAC twice daily for 14 days. The other untreated eyes served as controls. Schirmer test, fluorescein, and rose bengal staining were performe...
متن کاملCorneal Alternations Induced by Topical Application of Benzalkonium Chloride in Rabbit
Benzalkonium chloride (BAC) is the most common preservative in ophthalmic preparations. Here, we investigated the corneal alternations in rabbits following exposure to BAC. Twenty-four adult male New Zealand albino rabbits were randomly divided into three groups. BAC at 0.01%, 0.05%, or 0.1% was applied twice daily to one eye each of rabbits for 4 days. The contralateral untreated eyes were use...
متن کاملA mouse dry eye model induced by topical administration of benzalkonium chloride
PURPOSE To develop a dry eye model of mouse induced by topical administration of benzalkonium chloride (BAC) and investigate the possible mechanisms. METHODS BAC at concentration of 0.2% was applied to the mouse ocular surface for 7 days. Phenol red thread tear test, tear break-up time (BUT) test, corneal inflammatory index scoring, fluorescein and rose bengal test were performed to evaluate ...
متن کاملA mouse model of limbal stem cell deficiency induced by topical medication with the preservative benzalkonium chloride.
PURPOSE To develop a mouse model of limbal stem cell deficiency (LSCD) by topical administration of benzalkonium chloride (BAC). METHODS BAC solutions (0%-0.5%) were applied to the mouse ocular surface for 4 weeks. Corneal neovascularization, inflammation, and epithelial status were observed under slit-lamp microscope. The eyeball and ocular surface tissues were collected at 4 and 12 weeks an...
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ژورنال
عنوان ژورنال: Indian Dermatology Online Journal
سال: 2018
ISSN: 2229-5178
DOI: 10.4103/idoj.idoj_53_17